Research Outputs

Now showing 1 - 2 of 2
  • Publication
    Supportive care for end-stage kidney disease: An integral part of kidney services across a range of income settings around the world
    (Elsevier, 2020)
    Hole, Barnaby
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    Hemmelgarn, Brenda
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    Brown, Edwina
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    Brown, Mark
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    McCulloch, Mignon I.
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    Andreoli, Sharon P.
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    Blake, Peter G.
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    Couchoud, Cécile
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    Cueto Manzano, Alfonso M.
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    Dreyer, Gavin
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    García García, Guillermo
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    Jager, Kitty J.
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    McKnight, Marla
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    Morton, Rachael L.
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    Murtagh, Fliss E.M.
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    Naicker, Saraladevi
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    Obrador, Gregorio T.
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    Perl, Jeffrey
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    Rahman, Muhibur
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    Shah, Kamal D.
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    Van Biesen, Wim
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    Walker, Rachael C.
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    Yeates, Karen
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    Zemchenkov, Alexander
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    Zhao, Ming-Hui
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    Davies, Simon J.
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    Caskey, Fergus J.
    A key component of treatment for all people with advanced kidney disease is supportive care, which aims to improve quality of life and can be provided alongside therapies intended to prolong life, such as dialysis. This article addresses the key considerations of supportive care as part of integrated end-stage kidney disease care, with particular attention paid to programs in low- and middle-income countries. Supportive care should be an integrated component of care for patients with advanced chronic kidney disease, patients receiving kidney replacement therapy (KRT), and patients receiving non-KRT conservative care. Five themes are identified: improving information on prognosis and support, developing context-specific evidence, establishing appropriate metrics for monitoring care, clearly communicating the role of supportive care, and integrating supportive care into existing health care infrastructures. This report explores some general aspects of these 5 domains, before exploring their consequences in 4 health care situations/settings: in people approaching end-stage kidney disease in high-income countries and in low- and middle-income countries, and in people discontinuing KRT in high-income countries and in low- and middle-income countries.
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    Publication
    Conservative kidney management and kidney supportive care: Core components of integrated care for people with kidney failure
    (Elsevier, 2024) ;
    Davison, Sara
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    Pommer, Wolfgang
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    Brown, Mark
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    Douglas, Claire
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    Gelfand, Samantha
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    Gueco, Irmingarda
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    Hole, Barnaby
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    Homma, Sumiko
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    Kazancıoğlu, Rümeyza
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    Kitamura, Harumi
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    Koubar, Sahar
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    Krause, Rene
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    Li, Kelly
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    Lowney, Aoife
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    Nagaraju, Shankar
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    Niang, Abdou
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    Obrador, Gregorio
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    Ohtake, Yoichi
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    Schell, Jane
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    Scherer, Jennifer
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    Smyth, Brendan
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    Tamba, Kaichiro
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    Vallath, Nandini
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    Wearne, Nicola
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    Zakharova, Elena
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    Brennan, Frank
    Integrated kidney care requires synergistic linkage between preventative care for people at risk for chronic kidney disease and health services providing care for people with kidney disease, ensuring holistic and coordinated care as people transition between acute and chronic kidney disease and the 3 modalities of kidney failure management: conservative kidney management, transplantation, and dialysis. People with kidney failure have many supportive care needs throughout their illness, regardless of treatment modality. Kidney supportive care is therefore a vital part of this integrated framework, but is nonexistent, poorly developed, and/or poorly integrated with kidney care in many settings, especially in low- and middle-income countries. To address this, the International Society of Nephrology has (i) coordinated the development of consensus definitions of conservative kidney management and kidney supportive care to promote international understanding and awareness of these active treatments; and (ii) identified key considerations for the development and expansion of conservative kidney management and kidney supportive care programs, especially in low resource settings, where access to kidney replacement therapy is restricted or not available. This article presents the definitions for conservative kidney management and kidney supportive care; describes their core components with some illustrative examples to highlight key points; and describes some of the additional considerations for delivering conservative kidney management and kidney supportive care in low resource settings.