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Dr. Garrido-Méndez, Alex
Research Outputs
No cumplir con las recomendaciones de actividad física se asocia a mayores niveles de obesidad, diabetes, hipertensión y síndrome metabólico en población chilena
2018, Díaz-Martínez, Ximena, Petermann, Fanny, Leiva, Ana María, Garrido-Méndez, Alex, Salas-Bravo, Carlos, Martínez, María Adela, Labraña, Ana María, Duran, Eliana, Valdivia-Moral, Pedro, Zagalaz, María Luisa, Poblete-Valderrama, Felipe, Álvarez, Cristian, Celis-Morales, Carlos
Background: Physical inactivity is an important cardiovascular risk factor. Aim: To investigate the association of physical inactivity with obesity, metabolic markers, type 2 diabetes mellitus, hypertension and metabolic syndrome in Chilean adults. Material and Methods: Participants from the National Health Survey 2009-10 (n = 5,157) were included in this study. Body mass index, waist circumference, metabolic markers (blood glucose, glycosylated hemoglobin and lipid profile) were the outcomes. Type 2 diabetes, hypertension and metabolic syndrome were determined using international criteria. Physical activity levels were determined using the Global Physical Activity Questionnaire and physical inactivity was defined as < 600 METs/minutes/week. Results: Compared to their physically active peers, inactive men and women had a higher odds ratio (OR) for obesity (OR: 1.77 [95% confidence intervals (CI): 1.29-2.42], p < 0.01 and 1.25 [95% CI: 102-1.54], p < 0.035, respectively), diabetes (OR: 2.47 [1.80-3.38], p < 0.01 and 1.72 [1.35-2.19], p = 0.002, respectively) and hypertension (OR: 1.66 [1.31-2.09], p < 0.01 and 1.83 [1.54-2.18] respectively. An association of physical inactivity with central obesity and metabolic syndrome was observed only in men (OR: 1.92 [1.42- 2.58], p < 0.01 and 1.74 [1.23-2.47], p < 0.01, respectively). Conclusions: Not meeting the physical activity recommendations is associated with obesity, diabetes, hypertension and metabolic syndrome, which are important cardiovascular risk factors.
Adiposidad corporal, estilos de vida y nivel de actividad física en mujeres dueñas de casa y trabajadoras remuneradas chilenas
2019, Concha Cisternas, Yeny, Petermann-Rocha, Fanny, Vásquez-Gómez, Jaime A., Matus-Castillo, Carlos, Leiva, Ana María, Martínez, María Adela, Garrido-Méndez, Alex, Diaz-Martinez, Ximena, Molina-Sotomayo, Edgardo, Pavez-Adasme, Gustavo, Carrasco Beltrán, Hernaldo, Silva-Urra, Jaime, Beltran, Ana Rosa, Celis-Morales, Carlos
En Chile existe escasa evidencia en relación a las características de los estilos de vida en mujeres dueñas de casa versus mujeres con trabajos renumerados. El objetivo del estudio fue comparar marcadores de adiposidad, hábitos de consumo asociados a estilos de vida y nivel de actividad física (AF) en mujeres dueñas de casa y trabajadoras remuneradas chilenas. Se compararon variables de adiposidad como el índice de masa corporal (IMC), peso corporal, perímetro de cintura (PC), estilos de vida y niveles de AF (transporte, moderada y vigorosa intensidad y tiempo sedente) de 2.232 participantes de la Encuesta Nacional de Salud 2009-2010. Las dueñas de casa, en comparación con las trabajadoras renumeradas, presentaron un mayor IMC (27,9 vs. 20,0 kg/m2 , p<0,0001) y PC (98,3 vs. 95,6 cm, p<0,0001). El tiempo destinado a la práctica de AF de trasporte (42,5 vs. 51,5 min/día, p= 0,009), moderada (94,2 vs. 128,4 min/día, p<0,0001) y vigorosa (25,06 vs. 53,49 min/día, p<0,0001) fue menor en dueñas de casa que en trabajadoras renumeradas. Por el contrario, las dueñas de casa destinaron menor tiempo al desarrollo de actividades sedentes (2,71 vs. 3,26 horas/día, p<0,0001), además mostraron un menor consumo de alcohol (30,5 vs. 43,2 g/día, p= 0,021) en comparación a trabajadoras renumeradas.
Asociación entre diabetes mellitus tipo 2, historia familiar de diabetes y deterioro cognitivo en adultos mayores chilenos
2018, Petermann, Fanny, Troncoso-Pantoja, Claudia, Martínez, María Adela, Leiva, Ana María, Ramírez-Campillo, Rodrigo, Poblete-Valderrama, Felipe, Garrido-Méndez, Alex, Díaz-Martínez, Ximena, Ulloa, Natalia, Concha Cisternas, Yeny, Celis-Morales, Carlos
Background: Although cardiovascular risk factors are associated with an impaired cognitive function, the impact of diabetes on cognitive function in Chilean adults is unknown. Aim: To investigate the association of diabetes or family history of the disease with cognitive impairment in older adults. Materials and Methods: Data from the 2009-2010 Chilean National Health Survey including 1,384 participants aged ≥ 60 years were included in this study. A score below 13 points for the Mini Mental State Examination (MMSE) was considered an indication of cognitive impairment. Logistic regression analyses were performed to assess the association between MMSE, diabetes and family history of the disease. Results: Cognitive impairment increased with age (Odds ratio (OR): 1.83 [95% confidence intervals (CI): 1.53; 2.19], p < 0.01, per 5 years increment in age). This trend was greater in individuals with diabetes (OR: 2.37 [95% CI: 1.68; 3.35], p < 0.01) compared to those without the disease. A similar trend was identified among individuals with a family history of diabetes compared to those without. Conclusions: Older adults with diabetes are more susceptible to develop cognitive impairment.
Patterns of healthy lifestyle behaviours in older adults: Findings from the Chilean National Health Survey 2009–2010
2018, Troncoso-Pantoja, Claudia, Petermann-Rocha, Fanny, Brown, Rosemary, Leiva, Ana María, Martínez, María Adela, Díaz-Martínez, Ximena, Garrido-Méndez, Alex, Poblete-Valderrama, Felipe, Iturra-González, José A., Villagran-Orellana, Marcelo, Mardones-Leiva, Lorena, Salas-Bravo, Carlos, Ulloa, Natalia, García-Hermoso, Antonio, Ramírez-Vélez, Robinson, Vásquez Gómez, Jaime, Celis-Morales, Carlos
The purpose of this study was to investigate healthy lifestyle behaviours across age categories in the older population in Chile. Data from 1390 older adults (≥60 years), in the 2009–2010 Chilean National Health Survey were analyzed. We derived the following age categories: 60–65, 66–70, 71–75, 76–80 and >80 years. The associations between age and compliance with healthy lifestyle behaviours (smoking, sitting time, physical activity, sleep duration and intake of salt, alcohol, fruit and vegetables) were investigated using logistic regression. The probability of meeting the guidelines for alcohol intake (OR trend: 1.35 [95% CI: 1.11; 1.64], p = 0.001) and smoking (OR trend: 1.23 [95% CI: 1.13; 1.33], p < 0.0001) increased with age, whereas spending <4 h per day sitting time or engaging in at least 150 min of physical activity per week or sleep on average between 7 and 9 h per day were less likely to be met with increasing age (OR trend: 0.77 [95% CI: 0.71; 0.83], p < 0.000; OR trend: 0.73 [95% CI: 0.67; 0.79], p < 0.0001, and OR trend: 0.89 [95% CI: 0.82; 0.96], p = 0.002, respectively). No significant trend across age categories was observed for fruit and vegetables, and salt intake. The probability of meeting at least 3 out of 7 healthy lifestyle behaviours across the age categories was also lower in older age categories compared to those aged 60 to 65 years. Overall, in older adults the probability of having the healthy lifestyle behaviours of physical activity, sitting time and sleeping behaviours was low but not for smoking or alcohol consumption. With an increasingly ageing population, these findings could inform stakeholders on which lifestyle behaviours could be targeted in the older adults and therefore which interventions should take place to promote healthy ageing.
Sociodemographic patterns of urine sodium excretion and its association with hypertension in Chile: A cross-sectional analysis
2019, Petermann Rocha, Fanny, Sillars, Anne, Brown, Rosemary, Sweeney, Lauren, Troncoso-Pantoja, Claudia, García Hermoso, Antonio, Leiva, Ana María, Martínez, María Adela, Diaz Martínez, Ximena, Poblete Valderrama, Felipe, Garrido-Méndez, Alex, Cataldo, Ximena, Iturra Gonzalez, José, Salas, Carlos, Lara, José, Gray, Stuart R., Celis Morales, Carlos
Objective: The aim of the study was to determine the main factors (sociodemographic, anthropometric, lifestyle and health status) associated with high Na excretion in a representative population of Chile. Design: Na excretion (g/d), a valid marker of Na intake, was determined by urine analysis and Tanaka's formulas. Blood pressure was measured by trained staff and derived from the mean of three readings recorded after 15 min rest. The associations of Na excretion with blood pressure and the primary correlates of high Na excretion were determined using logistic regression. Setting: Chileans aged ≥15 years.ParticipantsParticipants (n 2913) from the Chilean National Health Survey 2009-2010. Results: Individuals aged 25 years or over, those who were obese and those who had hypertension, diabetes or metabolic syndrome were more likely to have higher Na excretion. The odds for hypertension increased by 10·2 % per 0·4 g/d increment in Na excretion (OR=1·10; 95 % CI 1·06, 1·14; P < 0·0001). These findings were independent of major confounding factors. Conclusions: Age, sex, adiposity, sitting behaviours and existing co-morbidities such as diabetes were associated with higher Na excretion levels in the Chilean population. These findings could help policy makers to implement public health strategies tailored towards individuals who are more likely to consume high levels of dietary salt.