Research Outputs

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Immersive Virtual Reality-Based Exercise for Pain Management in Fibromyalgia: An Exploratory Study with Risk of Poor Outcomes Stratification

2025, Carvajal-Parodi, Claudio, Arias-Álvarez, Gonzalo, Dr. Ulloa-Díaz, David, Romero-Vera, Luis, Andrades-Ramírez, Oscar, Guede-Rojas, Francisco, Ponce-González, Jesús G.

Fibromyalgia (FM) is characterized by persistent widespread pain that severely impacts quality of life. Immersive virtual reality-based exercise (iVRE) is emerging as a therapeutic modality for chronic pain management. However, research on iVRE in FM patients has primarily focused on perceived pain intensity (PI), with limited exploration of underlying analgesic mechanisms. This study aims to explore the effects of iVRE on PI, considering risk of poor outcomes (RPO) stratification, and on mechanical pain sensitivity (MPS) in FM. A single-arm, uncontrolled, pre-post-test exploratory study was conducted in subjects with FM. The intervention included 2 weekly 15-min iVRE sessions for 6 weeks. PI (numeric rating scale [NRS]) and MPS (pressure pain thresholds [PPTs] at the upper trapezius, lumbar spine, and knee) were assessed at baseline, after the first session (to assess exercise-induced hypoalgesia), and postintervention. RPO was assessed using the Keele STarT MSK Tool. Eleven participants completed the study. No adverse effects were reported. Clinically important reductions were observed in PI (mean difference [MD]: −2.36, 95% CI: [−4.15, −0.58], d = 0.89; p < 0.05) with this effect being associated with baseline RPO. No observable changes were found in PPTs (all 95% CIs included 0, p > 0.05). In this sample, iVRE appears to reduce PI but not PPTs, suggesting the persistence of MPS and limitations in activating endogenous pain inhibitory mechanisms. Further randomized controlled trials with larger samples are needed to corroborate these results.

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Efecto de los juegos reducidos en la composición corporal y la condición física aeróbica en un grupo de adolescentes escolares

2015, Carrasco Beltrán, Hernaldo, Reigal Garrido, Rafael E., Dr. Ulloa-Díaz, David, Chirosa Ríos, Ignacio Jesús, Chirosa Ríos, Luis Javier

The regular practice of physical activity contributes to weight control and improves maximal oxygen uptake (VO2max), socialization and quality of life. Aim: To determine the effect of moderate-to-vigorous physical activity on body composition and VO2max in a group of overweight school-age males. Material and Methods: We studied fifty-five overweight males aged 15.6 ± 0.7 years. Participants were divided in two groups (experimental and control groups). The intervention in the experimental group was the practice of small-sided games during 60 minutes, two days per week and during 11 weeks. At baseline and the end of the intervention, body composition was measured using bioimpedance and VO2max was calculated using the Course Navette test. Results: A 7% reduction in the percentage of body fat and a 9% increase in VO2max were observed in the experimental group (p < 0.01). No changes were recorded in the control group. Conclusions: Eleven weeks of small-sided exercises performed twice per week increased VO2max and reduced fat mass in overweight adolescents.