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Dr. Villagran-Orellana, Marcelo
Research Outputs
Association between a lifestyle score and all-cause mortality: A prospective analysis of the Chilean National Health Survey 2009–2010
2023, Dra. Mardones-Leiva, Lorena, Dra. Troncoso-Pantoja, Claudia, Dr. Villagran-Orellana, Marcelo, Petermann-Rocha, Fanny, Diaz-Toro, Felipe, MartÃnez-Sanguinetti, MarÃa Adela, Leiva-Ordoñez, Ana, Nazar, Gabriela, Concha-Cisternas, Yeny, DÃaz MartÃnez, Ximena, Lanuza, Fabian, Carrasco-MarÃn, Fernanda, Martorell, Miquel, RamÃrez-Alarcón, Karina, Labraña, Ana MarÃa, Parra-Soto, Solange, Lasserre-Laso, Nicole, Cigarroa, Igor, Vásquez-Gómez, Jaime, Celis-Morales, Carlos
Objective: To investigate the association between a lifestyle score and all-cause mortality in the Chilean population. Design: Prospective study. Settings: The score was based on seven modifiable behaviours: salt intake, fruit and vegetable intake, alcohol consumption, sleep duration, smoking, physical activity and sedentary behaviours. 1-point was assigned for each healthy recommendation. Points were summed to create an unweighted score from 0 (less healthy) to 7 (healthiest). According to their score, participants were then classified into: less healthy (0–2 points), moderately healthy (3–4 points) and the healthiest (5–7 points). Associations between the categories of lifestyle score and all-cause mortality were investigated using Cox proportional hazard models adjusted for confounders. Nonlinear associations were also investigated. Participants: 2706 participants from the Chilean National Health Survey 2009–2010. Results: After a median follow-up of 10·9 years, 286 (10·6 %) participants died. In the maximally adjusted model, and compared with the healthiest participants, those less healthy had 2·55 (95 % CI 1·75, 3·71) times higher mortality risk due to any cause. Similar trends were identified for the moderately healthy group. Moreover, there was a significant trend towards increasing the mortality risk when increasing unhealthy behaviours (hazard ratio model 3: 1·61 (95 % CI 1·34, 1·94)). There was no evidence of nonlinearity between the lifestyle score and all-cause mortality. Conclusion: Individuals in the less healthy lifestyle category had higher mortality risk than the healthiest group. Therefore, public health strategies should be implemented to promote adherence to a healthy lifestyle across the Chilean population.