Dra. Gerli-Candia, Lorena

Thumbnail Image
Nombre de publicación
Dra. Gerli-Candia, Lorena
Nombre completo
Gerli Candia, Lorena Andrea
Facultad
Email
loregerli@ucsc.cl
ORCID
Scopus Author ID
6506865225
Researcher ID
GLU-4473-2022

Filters

20211
Reset filters

Settings

Author: Cardona-Villada, Wilson × Subject: Nanocomposite ×

Research Outputs

Now showing 1 - 1 of 1
  • Thumbnail Image
    Publication
    Synthesis, chemical identification, drug release and docking studies of the Amlodipine–Chitosan nanobiopolymer composite
    (Journal of the Chilean Chemical Society, 2021)
    Dra. Gerli-Candia, Lorena 
    ;
    Ramirez-Tagle, Rodrigo
    ;
    Salgado-Moran, Guillermo
    ;
    Mendez-Luna, David
    ;
    Correa-Basurto, José
    ;
    Cardona-Villada, Wilson
    ;
    Mendoza-Huizar, Luis H.
    A new amlodipine-chitosan nanocomposite was built using amlodipine nanoparticles as primary scaffolds by spontaneous emulsification, and its complete elucidation was performed by using several spectrometric techniques. Our results indicate that the amlodipine-chitosan nanocomposite has better solubility than amlodipine at pH 7.4 with a nearly all the drug substance dissolved (97%) by the final time-point measured. The docking study support the existence of intermolecular interactions are established between amlodipine and chitosan