Research Outputs

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    Publication
    Association between a lifestyle score and all-cause mortality: A prospective analysis of the Chilean National Health Survey 2009–2010
    (Cambridge University Press, 2023) ; ; ;
    Petermann-Rocha, Fanny
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    Diaz-Toro, Felipe
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    Martínez-Sanguinetti, María Adela
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    Leiva-Ordoñez, Ana
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    Nazar, Gabriela
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    Concha-Cisternas, Yeny
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    Díaz Martínez, Ximena
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    Lanuza, Fabian
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    Carrasco-Marín, Fernanda
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    Martorell, Miquel
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    Ramírez-Alarcón, Karina
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    Labraña, Ana María
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    Parra-Soto, Solange
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    Lasserre-Laso, Nicole
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    Cigarroa, Igor
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    Vásquez-Gómez, Jaime
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    Celis-Morales, Carlos
    Objective: To investigate the association between a lifestyle score and all-cause mortality in the Chilean population. Design: Prospective study. Settings: The score was based on seven modifiable behaviours: salt intake, fruit and vegetable intake, alcohol consumption, sleep duration, smoking, physical activity and sedentary behaviours. 1-point was assigned for each healthy recommendation. Points were summed to create an unweighted score from 0 (less healthy) to 7 (healthiest). According to their score, participants were then classified into: less healthy (0–2 points), moderately healthy (3–4 points) and the healthiest (5–7 points). Associations between the categories of lifestyle score and all-cause mortality were investigated using Cox proportional hazard models adjusted for confounders. Nonlinear associations were also investigated. Participants: 2706 participants from the Chilean National Health Survey 2009–2010. Results: After a median follow-up of 10·9 years, 286 (10·6 %) participants died. In the maximally adjusted model, and compared with the healthiest participants, those less healthy had 2·55 (95 % CI 1·75, 3·71) times higher mortality risk due to any cause. Similar trends were identified for the moderately healthy group. Moreover, there was a significant trend towards increasing the mortality risk when increasing unhealthy behaviours (hazard ratio model 3: 1·61 (95 % CI 1·34, 1·94)). There was no evidence of nonlinearity between the lifestyle score and all-cause mortality. Conclusion: Individuals in the less healthy lifestyle category had higher mortality risk than the healthiest group. Therefore, public health strategies should be implemented to promote adherence to a healthy lifestyle across the Chilean population.
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    Publication
    Asociación de un índice de estilos de vida saludable con factores de riesgo cardiovascular en población chilena
    (Revista Médica de Chile, 2018)
    Leiva, Ana María
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    Petermann-Rocha, Fanny
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    Martínez-Sanguinett, María Adela
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    Concha Cisternas, Yeny
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    Díaz-Martínez, Ximena
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    Lanuza-Rilling, Fabián
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    Ulloa, Natalia
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    Martorell, Miquel
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    Álvarez, Cristian
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    Celis-Morales, Carlos
    Background: Healthy lifestyles are associated with a better metabolic and cardiovascular health profile. Aim: To investigate the association between a lifestyle score and cardiovascular risk in Chilean adults. Material and Methods: A healthy lifestyle score was derived for 2,774 participants in the Chilean National Health Survey 2009-2010 and based on seven modifiable behaviors (salt intake, fruit and vegetable intake, alcohol consumption, sleep duration, smoking, physical activity and sedentary behaviors). A high score represented a healthier lifestyle whereas a low score represents an unhealthy lifestyle. The association between the lifestyle score and cardiovascular risk factors (obesity, hypertension, diabetes, dyslipidemia and metabolic syndrome), was explored using logistic regression models. Results: One quartile increment in the healthy lifestyle score was associated with a lower risk for obesity (Odds ratio (OR): 0.82 [95% confidence intervals (CI): 0.75 to 0.90], p < 0.01), central obesity (OR: 0.88 [95% CI: 0.81 to 0.96], p < 0.01), diabetes (OR: 0.84 [95% CI: 0.75 to 0.95], p < 0.04) and dyslipidemia (OR: 0.90 [95% CI: 0.83 to 0.98], p = 0.01). These results were independent of major confounding factors. Conclusions: The adherence to a healthy lifestyle is associated with lower cardiovascular risk.