Anisotropy is an important characteristic of rocks, especially distinguishable in metamorphic rocks. Transverse isotropy is a particular case of anisotropy where foliation planes are distributed in the rock mass. Anisotropy can also originate from mineral foliation where minerals are oriented in a preferential direction. This inherent anisotropy can affect the rock strength significantly. Here the effect of foliation on the anisotropic strength of a phyllite is experimentally investigated. Phyllite specimens with defined foliation orientations are prepared and a series of laboratory tests carried out. Results for tensile strength and unconfined compressive strength are analysed. Maximum values of tensile strength and unconfined compressive strength are found for β = 0 and 90° and a significant reduction of strength is found for β = 45°. Compressive triaxial tests are conducted under confining pressures up to 20 MPa. The Hoek–Brown failure criterion is found to capture the experimental results in a better form than the Mohr–Coulomb criterion. Anisotropy indexes are adopted to evaluate the anisotropy effect on strength. Confinement is found to reduce the effect of anisotropy on phyllite strength. Cohesion and angle of shearing resistance were also found to be affected by the stress level, and further influenced by β.