Surface water samples from the environmental continuum spanning rivers (Petrohue, Cochamo, Puelo), fjord (Reloncaví), and the inner sea of Chiloé in Chilean Patagonia were analyzed to estimate concentration and distribution of dissolved Organochlorine pesticides (OCPs). High concentrations of HCHs, DDTs and endosulfan found in surface waters from rivers suggest that rivers are the major source of dissolved OCPs to coastal marine ecosystems. We interpret variations in the distribution and concentration as an apparent oscillation between rain and snow-scavenging processes that might determine the type of OCPs that can be preferentially deposited on mountains, glaciers, rivers, estuaries, and finally transferred to the marine realm. Predominance of α-HCH, γ-HCH, p,p′-DDE and α-endosulfan compounds suggest that the main deposition mechanism of OCPs to the Chilean Patagonia is rain scavenging. Snow and rain can be additional sources of OCPs that must be considered for future studies in fjord systems in Chilean Patagonia.