Blends of 1-hexene with alkoxyethanols have been studied in terms of intermolecular interactions. The investigated alkoxyethanols were 2-methoxyethanol or 2-ethoxyethanol or 2-butoxyethanol. This study was based on measurements of densities, ρ, speeds of sound, u, and refractive indices, nD, throughout the full range of composition. With the help of measured data, some derived/excess properties have been computed such as excess molar volume, VE m, isentropic compressibility,κs, deviation in isentropic compressibility, Δκs, and deviation in refractive indices, ΔnD and these properties were fitted to a Redlich Kister equation. Furthermore, PC-SAFT equation of state (PC-SAFT EoS) were used to correctly modeled the density of pure fluids and mixtures whereas the Nomoto’s relation modeled the speed of sound for the binary mixtures with the least deviation, while for the refractive index of all the mixtures, Laplace mixing rule was the best approach.