The present paper has the main aim to evaluate the competitive level of the regions of Mexico based on their performance on 10 main factors from 100 indicators. The methodology is based on the Multiple Criteria Hierarchy Process (MCHP) capable of analysing the performance of a subset and the comprehensive indicators, and how they impact the competitiveness of the region. An important aspect of the MCHP implemented is that it considers the interaction between criteria (indicators) and measure the performance of a large number of criteria. The main contribution to the research is with the identification of region with the worst level of competitiveness, and the factors are requiring more attention by the decision-makers.