Firms’ early internationalisation (EI) is a complex process derived from uncertain market conditions, entrepreneurial vision, and strategic entry decisions. Academic debates still require deepening and broadening the discussion on early internationalisation of new technology-based firms (NTBFs). This study proposes a framework to analyse how NTBFs are adopting collaborative networks with the triple helix actors (government, university, and industry) to implement an EI strategy in emerging economies. Our findings show that the lack of specialised knowledge and resources stimulates collaboration with multiple triple helix agents to ensure the early entry strategy into international markets. We state the relevant implications and propositions concerning the inter- nationalisation of NTBFs and the relationship with triple helix stakeholders.